My political opinions (more accurately described as rants), My family, and my multiple myeloma treatments. Hey, might as well put it down while I am on this side of the dirt... jc
Obama Supporter Interviews Her 2008 Self
Gee, if you read my posts from the past... I WOULD BE RIGHT!
Time to get a life.
jc
Why I don't want BHO reelected part 2
In a post today, I mention that there is a new treatment path open to me, should the cancer come back.
In BHO's world, I would have to go to Congress to get this new treatment approved for use... at a Congressional pace.
In BHO's world, I would have to go to Congress to get this new treatment approved for use... at a Congressional pace.
- Convince someone that it is a good idea. Not my doctor, not Kaiser, not my wife... but some bureaucrat or (most likely) a politician at the national level (Senator or House member).
- Get on the calendar. Along with all the other novel treatments, I will be heard (eventually), in order. Oh, and there will be no doctors on the panel.
- Get funded.
- get the bureaucratic rule writing done.
- Await implementation so my insurance (assuming that we were able to keep Kaiser - a "Cadillac" plan) can fund it through the government protocols.
- Get treated.
Oh, the fun we will have. Retaining lobbyist after lobbyist, flying to and fro for hearings, calling, e-mailing, waiting, and ultimately... not getting treated.
Yes, all my well being will come from that swamp that was mostly filled in, Washington D.C.
I need to take a pill...
jc
Why I don't want BHO reelected (part 1)
This note shows that he is anti civil rights, and just wants to grab all the guns he can. As Professor Reynolds says:" It's easier to make them beggars..."
New Multiple Myeloma treatment
Faster Please...
Source: J Clin Oncol | Posted 5 days ago
Bortezomib Induction and Maintenance Treatment in Patients With Newly Diagnosed Multiple Myeloma: Results of the Randomized Phase III HOVON-65/ GMMG-HD4 Trial; Sonneveld P, Schmidt-Wolf IG, van der Holt B, El Jarari L, Bertsch U, Salwender H, Zweegman S, Vellenga E, Broyl A, Blau IW, Weisel KC, Wittebol S, Bos GM, Stevens-Kroef M, Scheid C, Pfreundschuh M, Hose D, Jauch A, van der Velde H, Raymakers R, Schaafsma MR, Kersten MJ, van Marwijk-Kooy M, Duehrsen U, Lindemann W, Wijermans PW, Lokhorst HM, Goldschmidt HM; Journal of Clinical Oncology (JCO) (Jul 2012)
PURPOSE We investigated whether bortezomib during induction and maintenance improves survival in newly diagnosed multiple myeloma (MM).Patients And methodsIn all, 827 eligible patients with newly diagnosed symptomatic MM were randomly assigned to receive induction therapy with vincristine, doxorubicin, and dexamethasone (VAD) or bortezomib, doxorubicin, and dexamethasone (PAD) followed by high-dose melphalan and autologous stem-cell transplantation. Maintenance consisted of thalidomide 50 mg (VAD) once per day or bortezomib 1.3 mg/m(2) (PAD) once every 2 weeks for 2 years. The primary analysis was progression-free survival (PFS) adjusted for International Staging System (ISS) stage.ResultsComplete response (CR), including near CR, was superior after PAD induction (15% v 31%; P<.001) and bortezomib maintenance (34% v 49%; P<.001). After a median follow-up of 41 months, PFS was superior in the PAD arm (median of 28 months v 35 months; hazard ratio [HR], 0.75; 95% CI, 0.62 to 0.90; P = .002). In multivariate analysis, overall survival (OS) was better in the PAD arm (HR, 0.77; 95% CI, 0.60 to 1.00; P = .049). In high-risk patients presenting with increased creatinine more than 2 mg/dL, bortezomib significantly improved PFS from a median of 13 months to 30 months (HR, 0.45; 95% CI, 0.26 to 0.78; P = .004) and OS from a median of 21 months to 54 months (HR, 0.33; 95% CI, 0.16 to 0.65; P<.001). A benefit was also observed in patients with deletion 17p13 (median PFS, 12 v 22 months; HR, 0.47; 95% CI, 0.26 to 0.86; P = .01; median OS, 24 months v not reached at 54 months; HR, 0.36; 95% CI, 0.18 to 0.74; P = .003). CONCLUSIONBortezomib during induction and maintenance improves CR and achieves superior PFS and OS.
Malfeasance all around
We Californians are so screwed...
They budgeted 7.5% growth - in this economy. Guess what: it didn't happen.
Oh, and the money that they didn't "earn" will come out of the classroom. Texas anyone?
JULY 17, 2012
CALIFORNIA PENSION CRISIS UPDATE: Largest public pension fund earns dismal 1 percent. “The nation’s largest public pension fund collected a dismal 1 percent annual return on its investments, a figure far short of projections that will likely bring pressure on California’s state and local governments to contribute more money, officials said Monday. The return reported by the California Public Employees’ Retirement System was well below its projected return of 7.5 percent for the fiscal year that ended June 30 and is prompting administrators to consider changes to investment strategies.”
Key bit: “You just can’t rely on these optimistic assumptions that somehow the investment returns are going to be so great that you don’t have to worry about paying for this stuff.” Things that can’t go on forever, won’t. Debts that can’t be paid, won’t be.
http://www.sfgate.com/news/article/Largest-public-pension-fund-earns-dismal-1-percent-3710740.php
I have a school fundraiser to plan...
jc
What's going on in California?
As a CSUF Alumni, it is sad to see the pathetic state of education around here.
It started a long time ago - CSUF built a new stadium for football (I only knew one football player there the whole time I was there), then canceled the program because it couldn't afford it.
As I go on campus now, there are shinny new student centers, a parking lot with a pool, and buildings all around... but do they graduate?
Go Titans...
Please.
jc
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